Hydrochloric Acid → HCID 86686076, compound

HRID 400467Notes

Reaction equation

HRID 400467 reaction equation
C(OC([CH:8]1[CH2:14][CH2:13][N:12]2[C:15]([CH3:18])=[CH:16][N:17]=[C:11]2[CH2:10][NH:9]1)=O)(C)(C)C.[ClH:19]>O1CCOCC1>[ClH:19].[ClH:19].[CH3:18][C:15]1[N:12]2[CH2:13][CH2:14][CH2:8][NH:9][CH2:10][C:11]2=[N:17][CH:16]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86686078HCID 86686078, compound

Product 1

HCID 86686076HCID 86686076, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1.89 g 3-methyl-5,6,8,9-tetrahydro-imidazo[1,2-a][1,4]diazepine-7-carboxylic acid tert-butyl ester was stirred in 40 mL 4 mol/L HCl solution in dioxane over night. The mixture was concentrated to give 1.67 g of the desired product. Rt: 0.62 min (method AC), (M+H)+: 152

Workup

  1. concentrationThe mixture was concentrated

Sources & evidence

ORD record
ord-f883dca4e8a34f468c562b3c16b77f06
Source dataset
uspto-grants-2014_06
Patent number
US08741892B2

Reaction notes

Loading…