反应详情

温度

130 °C

7-Naphthalen-2-yl-7,9-diaza-bicyclo[4.2.2]dec-3-ene-8,10-dione (130 mg, 0.45 mmol) and DiBAl-H (6 mL, 1M, 6 mmol) were placed in a μW tube under argon vent. The reaction mixture was then heated to 130° C. for 900 sec. The reaction was quenched with Rochelle's salt and diethyl ether mixture (1:1, 200 mL) and then stirred overnight. The organic eas layer separated and dried with magnesium sulfate, filtered and solvent evaporated under reduced pressure to yield the title compound as a residue.

1. customThe reaction was quenched with Rochelle's salt and diethyl ether mixture (1:1, 200 mL)
2. customThe organic eas layer separated
3. dry with materialdried with magnesium sulfate
4. filtrationfiltered
5. customsolvent evaporated under reduced pressure