Methanol → HCID 66895060, compound

HRID 409612Notes

Reaction equation

HRID 409612 reaction equation
[NH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1C=O.[CH:13]1([NH2:23])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1.[CH3:24]O>>[NH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[CH:24]=[N:23][CH:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:16][CH2:15][CH2:14]2)[CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 887MethanolHCID 180661,2,3,4-Tetrahydro-1-naphthylamineHCID 19358683HCID 19358683, compound

Product 1

HCID 66895060HCID 66895060, compoundYield 70%

Procedure

0.57 g of tetrahydroquinolino aldehyde was dissolved in 10 ml of methanol and then 0.51 ml of 1,2,3,4-tetrahydro naphthyl amine was slowly added thereto. The resulting mixture was stirred at room temperature overnight before some precipitates were slowly formed. Then, the resulting mixture was filtered while being washed with methanol to provide ivory solids as a clean product (0.72 g). (Yield: 70%)

Workup

  1. customwere slowly formed
  2. filtrationThen, the resulting mixture was filtered
  3. washwhile being washed with methanol

Sources & evidence

ORD record
ord-94e31b54b11b4b00a907007907c45b94
Source dataset
uspto-grants-2014_06
Patent number
US08759461B2

Reaction notes

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