反应详情

To Compound 4 (2 g, 9.5 mmol), SOCl2 (9.8 ml, 134 mmol) and DMF (0.8 mL, 10 mmol) was added at room temperature. The reaction mixture heated to reflux for 15 min. The solvent was removed under reduced pressure. The crude oil was azeotroped with xylene twice.

1. temperatureThe reaction mixture heated
2. temperatureto reflux for 15 min
3. customThe solvent was removed under reduced pressure
4. customThe crude oil was azeotroped with xylene twice