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HRID410855

反应详情

EQUATION

反应方程式

HRID 410855 的结构方程式

REACTANTS

反应物

4
结构：CN
HCID6329

Methylamine

CH5N

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F
HCID2733084

Methanaminium, N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methyl-, hexafluorophosphate(1-) (1:1)

C11H16F6N5OP

结构：Cn1c(Nc2nc3cc(F)ccc3s2)nc2cc(C(=O)O)ccc21
HCID58397592

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)c1ccc2c(c1)nc(Nc1nc3cc(F)ccc3s1)n2C
HCID58397788

未命名化合物

收率 68%

PROCEDURE

实验过程

2-(5-Fluoro-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid methylamide (24 mg) was prepared by following General Procedure F using 2-(5-fluoro-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid (34 mg), methylamine (0.2 ml, 2.0 M solution in THF), HBTU (38 mg), and DIEA (0.1 ml). LCMS: m/z 357.