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HRID411002

反应详情

EQUATION

反应方程式

HRID 411002 的结构方程式

REACTANTS

反应物

3
结构：ClCCCl
HCID11

1,2-Dichloroethane

C2H4Cl2

结构：Nc1nc2ccc(OC(F)(F)F)cc2s1
HCID5070

6-(Trifluoromethoxy)-2-Benzothiazolamine

C8H5F3N2OS

结构：CCOC(=O)c1ccc(N)c(NC)c1
HCID67332734

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1ccc2nc(Nc3nc4ccc(OC(F)(F)F)cc4s3)n(C)c2c1
HCID86656914

未命名化合物

收率 59.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

3-Methyl-2-(6-trifluoromethoxy-benzothiazol-2-ylamino)-3H-benzoimidazole-5-carboxylic acid ethyl ester (2.8 g) was prepared by following General Procedure D starting from 6-trifluoromethoxy-benzothiazol-2-ylamine (2.9 g), 4-amino-3-methylamino-benzoic acid ethyl ester (2.1 g), thioCDI (2.2 g) and EDC (2.4 g) in DMF (30 mL).