Hydrochloric Acid → HCID 18536127, compound

HRID 412187Notes

Reaction equation

HRID 412187 reaction equation
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][S:13]([CH3:16])(=[O:15])=[O:14])=[CH:9][CH:10]=2)[C:5]([NH:17]C(OC(C)(C)C)=O)=[CH:4][CH:3]=1.[ClH:25]>C(OCC)(=O)C>[ClH:25].[NH2:17][C:5]1[C:6]2[C:11](=[CH:10][CH:9]=[C:8]([O:12][S:13]([CH3:16])(=[O:15])=[O:14])[CH:7]=2)[C:2]([Br:1])=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18536179HCID 18536179, compound

Product 1

HCID 18536127HCID 18536127, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of the product from Step C (4.60 g, 11.0 mmol) in ethyl acetate (200 mL) was saturated with HCl gas. The solution was stirred for 30 hours and then concentrated in vacuo to yield the titled compound as a brown solid.

Workup

  1. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-372b1eebfd284c0a9b53efe56a5539c7
Source dataset
uspto-grants-2003_05
Patent number
US06562823B1

Reaction notes

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