Dimethyl Sulfate → HCID 15451025, compound

HRID 412986Notes

Reaction equation

HRID 412986 reaction equation
[CH2:1]([N:3]([CH2:20][CH3:21])[CH2:4][CH2:5][O:6][C:7]1[CH:12]=[C:11]([N+:13]([O-:15])=[O:14])[CH:10]=[CH:9][C:8]=1[NH:16][C:17](=[O:19])[CH3:18])[CH3:2].[S:22]([O:27]C)([O:25][CH3:26])(=[O:24])=[O:23]>C(OCC)(=O)C>[CH3:26][O:25][S:22]([O-:27])(=[O:24])=[O:23].[C:17]([NH:16][C:8]1[CH:9]=[CH:10][C:11]([N+:13]([O-:15])=[O:14])=[CH:12][C:7]=1[O:6][CH2:5][CH2:4][N+:3]([CH2:1][CH3:2])([CH2:20][CH3:21])[CH3:26])(=[O:19])[CH3:18]

Participants

4

Reactant 2

HCID 6497Dimethyl SulfateHCID 15451024HCID 15451024, compound

Product 1

HCID 15451025HCID 15451025, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The quaternization of 59.1 g (0.2 mol) of N-[2-(2-diethylaminoethoxy)-4-nitrophenyl]acetamide dissolved in 700 ml of ethyl acetate was carried but by adding 20.9 ml (0.22 mol) of dimethyl sulphate with stirring for one hour at room temperature.

Sources & evidence

ORD record
ord-386e8a9b08d446c898313b9130d70bc3
Source dataset
uspto-grants-2003_05
Patent number
US06565614B1

Reaction notes

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