Potassium Carbonate → HCID 18522074, compound

HRID 413751Notes

Reaction equation

HRID 413751 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].C(=O)([O-])[O-].[K+].[K+].CN1CCCC1=O.[C:24]1([NH:30][CH2:31][CH2:32][NH2:33])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>O>[C:24]1([NH:30][CH2:31][CH2:32][NH:33][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[N+:8]([O-:10])=[O:9])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

6

Reactant 4

HCID 11430Potassium CarbonateHCID 13387N-methyl-2-pyrrolidoneHCID 738951-Fluoro-2-nitrobenzeneHCID 742701,2-Ethanediamine, N1-phenyl-

Product 1

HCID 18522074HCID 18522074, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 1-fluoro-2-nitrobenzene(15.5 g, 110 mmol) and potassium carbonate (15.2 g, 110 mmol) was stirred and a mixture of N-methylpyrrolidone (20 ml) and N-phenylethylenediamine (15.0 g, 110 mmol) was added over 1 h at room temperature. The mixture was stirred for 1 h. Water (200 ml) was added crystals were filtered off and triturated with petroleum ether. Yield 14.7 g, 52%. M.p. 64-66° C.

Workup

  1. additionwas added over 1 h at room temperature
  2. stirringThe mixture was stirred for 1 h
  3. filtrationwere filtered off
  4. customtriturated with petroleum ether

Sources & evidence

ORD record
ord-33bf4916cb6e4166beb4b965d35cb071
Source dataset
uspto-grants-2003_05
Patent number
US06569880B2

Reaction notes

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