Cyanoacetamide → HCID 21282644, compound

HRID 414088Notes

Reaction equation

HRID 414088 reaction equation
[Cl:1][C:2]1[C:11]([Cl:12])=[CH:10][CH:9]=[CH:8][C:3]=1[CH2:4][N:5]=[N+:6]=[N-:7].[C:13]([CH2:15][C:16]([NH2:18])=[O:17])#[N:14]>C(O)C>[NH2:14][C:13]1[N:5]([CH2:4][C:3]2[CH:8]=[CH:9][CH:10]=[C:11]([Cl:12])[C:2]=2[Cl:1])[N:6]=[N:7][C:15]=1[C:16]([NH2:18])=[O:17]

Participants

4

Reactant 2

HCID 7898CyanoacetamideHCID 21282659HCID 21282659, compound

Product 1

HCID 21282644HCID 21282644, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner analogous to that described in Example 2, by reacting 2,3-dichlorobenzyl azide with cyanoacetamide there is obtained 5-amino-1-(2,3-dichlorobenzyl)-1H-1,2,3-triazole-4-carboxamide having a melting point of 224°-226° (from ethanol). The starting material can be produced from 2,3-dichlorobenzyl alcohol as starting material by halogenation, for example with phosphorus tribromide, and reaction with sodium azide.

Sources & evidence

ORD record
ord-f78d030ed44f4c9d84dad5b4c4c1b530
Source dataset
uspto-grants-1988_12
Patent number
US04789680

Reaction notes

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