Water → HCID 21281403, compound

HRID 414616Notes

Reaction equation

HRID 414616 reaction equation
[C:1]1([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=[CH:5][C:4]([O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]Cl)=[CH:3][CH:2]=1.[C:21]1(=[O:31])[NH:25][C:24](=[O:26])[C:23]2=[CH:27][CH:28]=[CH:29][CH:30]=[C:22]12.[K].O>CN(C)C=O>[C:1]1([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:6]=[CH:5][C:4]([O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N:25]2[C:24](=[O:26])[C:23]3=[CH:27][CH:28]=[CH:29][CH:30]=[C:22]3[C:21]2=[O:31])=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 962WaterHCID 21281389HCID 21281389, compoundHCID 24194345Phthalimide potassium salt

Product 1

HCID 21281403HCID 21281403, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 1-(4-biphenyloxy)-6-chlorohexane (10.0 g) and potassium phthalimide (9.0 g) in dimethylformamide (100 ml) was heated at 140° C. for 4 hours. The cooled solution was poured into water (900 ml) and filtered to yield N-[6-(4-biphenyloxy) hexyl]phthalimide. (b) In a similar manner, but using the appropriate corresponding optionally substituted 1-(3- or 4-biphenyloxy)-ω-chloroalkane, obtained as described in Preparation 4, the following compounds of Formula C were prepared:

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-bfcb2722765b4cfb876af515ac29a558
Source dataset
uspto-grants-1988_12
Patent number
US04792570

Reaction notes

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