Phenol → o-(Methylthio)phenol

HRID 414666Notes

Reaction equation

HRID 414666 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:8][S:9]C1C=CC(O)=CC=1>>[CH3:8][S:9][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[OH:7]

Participants

3

Reactant 2

HCID 996PhenolHCID 140864-(Methylthio)phenol

Product 1

HCID 61261o-(Methylthio)phenolYield 41%

Procedure

The mixture was cooled to room temperature and filtered. The catalyst was washed several times with ether and allowed to dry. The filtrate and ether washings were combined, and volatiles were removed on a rotary flash evaporator. GC analysis indicated the presence of phenol (5.3 g. 42% recovered), ortho(methylthio)phenol (5.2 g. 41% yield), para-(methylthio)phenol (2.0 g, and di-(methylthio)phenols (2.0 g).

Workup

  1. filtrationfiltered
  2. washThe catalyst was washed several times with ether
  3. customto dry
  4. customvolatiles were removed on a rotary flash evaporator

Sources & evidence

ORD record
ord-f0b963b8906f4ca48af00e7e02df47d0
Source dataset
uspto-grants-1988_12
Patent number
US04792633

Reaction notes

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