Hydrazine hydrate (1:1) → HCID 136174321, compound

HRID 415944Notes

Reaction equation

HRID 415944 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[CH:4][C:3]=1[C:17](=O)[CH2:18][C:19](=O)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].O.[NH2:32][NH2:33]>C(O)C>[CH2:8]([C:5]1[CH:6]=[CH:7][C:2]([OH:1])=[C:3]([C:17]2[CH:18]=[C:19]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[NH:33][N:32]=2)[CH:4]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 59866349HCID 59866349, compound

Product 1

HCID 136174321HCID 136174321, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-(2-hydroxy-5-nonyl-phenyl)dodecane-1,3-dione (0.1 M) dissolved in ethanol (50 ml), hydrazine hydrate (0.105M) added and the reaction solution heated to reflux. Held at reflux for 2 hours, cooled to ambient and organic phase washed with water (2×25 ml). Toluene removed by vacuum evaporation to produce a brown oil.

Workup

  1. temperaturethe reaction solution heated to reflux
  2. temperatureHeld at reflux for 2 hours
  3. temperaturecooled to ambient and organic phase
  4. washwashed with water (2×25 ml)
  5. customToluene removed by vacuum evaporation
  6. customto produce a brown oil

Sources & evidence

ORD record
ord-e0766be59bc64163a82779140fcc5e28
Source dataset
uspto-grants-2012_01
Patent number
US08088810B2

Reaction notes

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