1-Methoxycarbonyl-2-isopropylidene hydrazine → Methyl 2-isopropylhydrazinecarboxylate

HRID 417614Notes

Reaction equation

HRID 417614 reaction equation
[CH3:1][O:2][C:3]([NH:5][N:6]=[C:7]([CH3:9])[CH3:8])=[O:4]>C(O)C.C(O)(=O)C.O=[Pt]=O>[CH3:1][O:2][C:3]([NH:5][NH:6][CH:7]([CH3:9])[CH3:8])=[O:4]

Participants

5

Reactant 1

HCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine

Product 1

HCID 57863323Methyl 2-isopropylhydrazinecarboxylateYield 77.6%

Reagents, catalysts & solvents 3

HCID 345198Adams' catalystCatalystHCID 176Acetic AcidSolventHCID 702EthanolSolvent

Procedure

N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g) were dissolved in ethanol (50 mL) and acetic acid (50 mL). PtO2 (0.231 g) was added, and reaction was stirred at room temperature for 22 hours under an atmosphere of hydrogen. Mixture was evaporated under vacuum, giving N′-Isopropyl-hydrazine-carboxylic acid methyl ester (5.08 g, 77%) as a white solid.

Workup

  1. customreaction
  2. customMixture was evaporated under vacuum

Sources & evidence

ORD record
ord-3d4be84114a5432786f6919c3c67770e
Source dataset
uspto-grants-2012_01
Patent number
US08088368B2

Reaction notes

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