反应详情

3-chloroperbenzoic acid (19 g) was added portionwise to an ice-cold solution of 2-phenylpyridine (10 g) in DCM (30 ml). The mixture was allowed to warm to RT and was stirred at RT for 4 h. 100 ml of a NaHCO3 solution were added to the reaction mixture and the phases were separated. The aq. phase was further extracted with DCM and the combined org. phases were washed with an aq. NaHSO3 (40%) solution and evaporated off. Recrystallisation (EA) afforded 8.77 g of the desired compound.

1. customthe phases were separated
2. extractionThe aq. phase was further extracted with DCM
3. washphases were washed with an aq. NaHSO3 (40%) solution
4. customevaporated off
5. customRecrystallisation (EA)