Methanol → 854919-87-2

HRID 418477Notes

Reaction equation

HRID 418477 reaction equation
[CH3:1][C:2]1([CH3:13])[CH2:7][CH2:6][C:5]([CH2:9][N+:10]([O-])=O)([OH:8])[CH2:4][CH2:3]1.CO>[OH-].[Pd+2].[OH-]>[NH2:10][CH2:9][C:5]1([OH:8])[CH2:6][CH2:7][C:2]([CH3:1])([CH3:13])[CH2:3][CH2:4]1

Participants

4

Reactant 2

HCID 887MethanolHCID 59845732HCID 59845732, compound

Product 1

HCID 59845710854919-87-2

Reagents, catalysts & solvents 1

HCID 9942167Palladium hydroxideCatalyst

Procedure

A mixture of 4,4-dimethyl-1-(nitromethyl)cyclohexanol (1.5 g, 0.0072 mol) and palladium hydroxide (0.1 g, 0.0001 mol) in methanol (50 mL, 1 mol) was stirred under hydrogen (1 atm) at room temperature overnight. The mixture was filtered and concentrated to afford the desired product as a clear oil. (1.08 g, 95%).

Workup

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-90974ff8a87f410cbd97398b24b09c90
Source dataset
uspto-grants-2012_01
Patent number
US08093265B2

Reaction notes

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