反应详情

4-Nitro-1-phenyl-1H-indazole (Intermediate 7) was dissolved in EtOAc (200 mL) then 10% Pd/C (500 mg) was added and the mixture was stirred under a hydrogen atmosphere for 2 hours. Filtration through Celite and concentration of the filtrate gave a yellow oil which was dissolved in ether (100 mL). A solution of 4N HCl in dioxan (10 mL) was added slowly resulting in a yellow precipitate which was filtered off to give the title compound as a yellow solid (2.5 g).

1. filtrationFiltration through Celite and concentration of the filtrate
2. customgave a yellow oil which
3. customresulting in a yellow precipitate which
4. filtrationwas filtered off