反应详情

温度

120 °C

9.30 g of 6-chloro-1H,3H-benzo[de]isochromene-1,3-dione and 4.46 g of cystamine hydrochloride were suspended in 50 ml of N-methylpyrrolidone (NMP). 5.5 g of diisopropylethylamine were added and the mixture was heated, with stirring, at 120° C. After 2 hours, 50 ml of NMP were added and the mixture continued to be stirred at 120° C. for 3 h. After cooling, the precipitated product was recovered, the filtered solution was extended by addition of 200 ml of water and a second precipitate was recovered. The precipitates were washed in water and dried. 11.46 g of white powder were recovered. The analyses showed that the product conformed to the expected structure.

1. temperaturethe mixture was heated
2. stirringto be stirred at 120° C. for 3 h
3. temperatureAfter cooling
4. customthe precipitated product was recovered
5. additionthe filtered solution was extended by addition of 200 ml of water
6. customa second precipitate was recovered
7. washThe precipitates were washed in water
8. customdried
9. custom11.46 g of white powder were recovered