Ethylene → HCID 86615047, compound

HRID 421004Notes

Reaction equation

HRID 421004 reaction equation
[C:1]([OH:6])(=[O:5])/[CH:2]=[CH:3]/[CH3:4].O.[PH2:8]([O-:10])=[O:9].[Na+].[CH2:12]=[CH2:13]>OO.O>[CH2:12]([P:8]([OH:10])([CH:3]([CH3:4])[CH2:2][C:1]([OH:6])=[O:5])=[O:9])[CH3:13]

Participants

6

Reactant 3

HCID 6325EthyleneHCID 637090Crotonic AcidHCID 178418950HCID 178418950, compound

Product 1

HCID 86615047HCID 86615047, compoundYield 58%

Reagents, catalysts & solvents 2

HCID 784Hydrogen PeroxideSolvent2×HCID 962WaterSolvent

Procedure

Using the method of Example 2, 516 g (6 mol) of crotonic acid were first admixed, at from 75 to 90° C. in the presence of 73.4 g of a 7% strength hydrogen peroxide solution, with 636 g (6 mol) of sodium hypophosphite monohydrate dissolved in 860 g of water. The resultant reaction mixture was then reacted with ethylene in the presence of 73.4 g of a 7% strength hydrogen peroxide solution. Appropriate work-up gave 623 g (58% of theory) of 3-(ethylhydroxyphosphinyl)butyric acid as colorless solid; chlorine content: <0.1 ppm.

Workup

  1. customThe resultant reaction mixture

Sources & evidence

ORD record
ord-b68e068aef9c493787e7fd4b79f749a5
Source dataset
uspto-grants-2012_01
Patent number
US08097753B2

Reaction notes

Loading…