反应详情

A stirred solution of 6-bromo-1′-(diphenylmethyl)spiro[1-benzofuran-3,3′-indol]-2′(1H)-one (2.5 g, 5.2 mmol), triethylsilane (5.0 mL) and trifluoroacetic acid (15.0 mL) was refluxed for 14 h. The solution was concentrated in vacuo and precipitated from hexanes to afford 6-bromospiro[1-benzofuran-3,3′-indol]-2′(1′H)-one (1.47 g, 89%) as a colorless solid: MS (ES+) m/z 316.1 (M+1), 318.1 (M+1).

1. concentrationThe solution was concentrated in vacuo
2. customprecipitated from hexanes