Sodium Sulfite → HCID 67162120, compound

HRID 42355Notes

Reaction equation

HRID 42355 reaction equation
[O-]S([O-])=O.[Na+:5].[Na+].C([O-])(O)=O.[Na+].[Br:12][C:13]1[CH:14]=[CH:15][C:16]([O:23][CH3:24])=[C:17]([S:19](Cl)(=[O:21])=[O:20])[CH:18]=1>O.O1CCOCC1>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([O:23][CH3:24])=[C:17]([S:19]([O-:21])=[O:20])[CH:18]=1.[Na+:5]

Participants

6

Reactant 3

HCID 24437Sodium SulfiteHCID 516892Sodium BicarbonateHCID 5200205-Bromo-2-methoxybenzene-1-sulfonyl chloride

Product 1

HCID 67162120HCID 67162120, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Conditions

Temperature
70 °C

Procedure

To a solution of Na2SO3 (1.42 g) and NaHCO3 (0.948 g) in H2O (17 ml) at 70° C. was added a solution of 5-bromo-2-methoxybenzene-1-sulfonyl chloride (2 g) in dioxane (17 ml) dropwise. The reaction mixture was stirred at 70° C. for 80 minutes and cooled to room temperature. The solvent was removed under vacuum to yield sodium 5-bromo-2-methoxybenzenesulfinate as white solid. The solid was placed under high vacuum overnight and used without further purification.

Workup

  1. temperaturecooled to room temperature
  2. customThe solvent was removed under vacuum

Sources & evidence

ORD record
ord-af953d32c592450796c85f7988a72c99
Source dataset
uspto-grants-2013_09
Patent number
US08536187B2

Reaction notes

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