反应详情

温度

60 °C

Pd—C 10% was added to a solution of 5 (200 mg, 0.27 mmol) and ammonium formate (0.75 g, 12.0 mmol) in methanol (10.0 mL) and the mixture was stirred at 60° C. for 1 h. The catalyst was removed and the methanolic solution was concentrated to give the amine 6 as an oil, which was dried under vacuum to give a foamy solid. Yield: 95 mg (92%).

1. customThe catalyst was removed
2. concentrationthe methanolic solution was concentrated