Ammonia → 2-(Dimethylamino)ethane-1-sulfonamide

HRID 424672Notes

Reaction equation

HRID 424672 reaction equation
[NH3:1].[CH3:2][N:3]([CH3:10])[CH2:4][CH2:5][S:6](Cl)(=[O:8])=[O:7]>C1COCC1>[CH3:2][N:3]([CH3:10])[CH2:4][CH2:5][S:6]([NH2:1])(=[O:8])=[O:7]

Participants

4

Reactant 2

HCID 222Ammonia2×HCID 142196572-(Dimethylamino)ethanesulfonyl chloride

Product 1

HCID 122768932-(Dimethylamino)ethane-1-sulfonamide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Ammonia was cautiously added to a cooled solution of the subtitle product of step ii) in THF (50 ml) and stirring maintained until all of the ammonia had evaporated before filtering off the product as a white solid. Yield: 0.88 g.

Workup

  1. customhad evaporated
  2. filtrationbefore filtering off the product as a white solid

Sources & evidence

ORD record
ord-ffdbe8a39e1749f88ff69dee7676fee7
Source dataset
uspto-grants-2012_01
Patent number
US08106063B2

Reaction notes

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