Hydrochloric Acid → 3-Methyl-2-phenethyl-4-phenyl-1,2,3,4-tetrahydro-benzo(b)-thieno[3,2-c]pyridine

HRID 426934Notes

Reaction equation

HRID 426934 reaction equation
[CH2:1](Br)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:10][CH:11]1[C:15]23[CH:23]([C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[CH:22]=[CH:21][CH:20]=[C:16]2[N:17]=[CH:18][CH:19]=[C:14]3[S:13][CH2:12]1.Cl>C(O)(C)C.CO>[CH3:10][CH:11]1[C:15]23[CH:23]([C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)[CH:22]=[CH:21][CH:20]=[C:16]2[N:17]=[CH:18][CH:19]=[C:14]3[S:13][CH:12]1[CH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 7666Phenethyl bromideHCID 203889093-Methyl-4-phenyl-1,2,3,4-tetrahydro-benzo(b)-thieno[3,2-c]-pyridine

Product 1

HCID 203889013-Methyl-2-phenethyl-4-phenyl-1,2,3,4-tetrahydro-benzo(b)-thieno[3,2-c]pyridine

Reagents, catalysts & solvents 1

HCID 21255859Isopropanol methanolSolvent

Procedure

Phenethyl bromide is condensed with 3-methyl-4-phenyl-1,2,3,4-tetrahydro-benzo(b)thieno[3,2-c]pyridine (Example 2) according to the procedure described in Example 6. Hydrochloride: white crytals, m.p. 210° C. (isopropanol-methanol); Yield : 72%.

Sources & evidence

ORD record
ord-d5bfeaaab62c4afbb40c271b1eb5066c
Source dataset
uspto-grants-1979_10
Patent number
US04172134

Reaction notes

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