反应详情

Ethereal hydrogen chloride is added dropwise to a stirred solution of 1.0 g. of 1-[2-(2-naphthyl)-2-(methoxy)ethyl]imidazole in 100 ml. of anhydrous ether until precipitation is complete. The product is filtered off, washed with ether, air dried and recrystallized from ethyl acetate/methanol to yield 1-[2-(2-naphthyl)-2-(methoxy)ethyl]imidazole hydrochloride, m.p. 171.5°-172.5° C.

1. customof anhydrous ether until precipitation
2. filtrationThe product is filtered off
3. washwashed with ether, air
4. customdried
5. customrecrystallized from ethyl acetate/methanol