反应详情

Starting from 2-cyclopropyl-4-methoxybenzothiazole-7-carboxylic acid (270 mg), p-nitrophenol (165 mg), and 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride (228 mg) in dichloromethane (35 ml). Trituration ofthe residue with diethyl ether yielded the title compound as a bright yellow solid (290 mg). TLC Rf 0.60 (ethyl acetate).