反应详情

To a solution of methyl 4-(1-methoxy-1-methylethyl)benzoate (120 mg, 0.57 mmol) in tetrahydrofuran (6 mL) and methanol (2 mL) was added 1 M aqueous lithium hydroxide (2 mL). After stirring for 2 h, the reaction mixture was diluted with diethyl ether and washed with 1 N hydrochloric acid (4 mL) and water (4 mL). The organic layer was dried (magnesium sulfate), filtered, and concentrated in vacuo to give 93 mg (84%) of the title compound.

1. washwashed with 1 N hydrochloric acid (4 mL) and water (4 mL)
2. dry with materialThe organic layer was dried (magnesium sulfate)
3. filtrationfiltered
4. concentrationconcentrated in vacuo