Lithium hydroxide, monohydrate → HCID 23708083, compound

HRID 428218Notes

Reaction equation

HRID 428218 reaction equation
[OH:1][C:2]1[CH:10]=[C:9]([C:11]#[C:12][CH2:13][C:14]2[CH:23]=[CH:22][C:21]3[C:20]([CH3:25])([CH3:24])[CH2:19][CH2:18][C:17]([CH3:27])([CH3:26])[C:16]=3[CH:15]=2)[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].O.[OH-].[Li+:30].[Li]>>[OH:1][C:2]1[CH:10]=[C:9]([C:11]#[C:12][CH2:13][C:14]2[CH:23]=[CH:22][C:21]3[C:20]([CH3:25])([CH3:24])[CH2:19][CH2:18][C:17]([CH3:27])([CH3:26])[C:16]=3[CH:15]=2)[CH:8]=[CH:7][C:3]=1[C:4]([O-:6])=[O:5].[Li+:30]

Participants

4

Reactant 3

HCID 168937Lithium hydroxide, monohydrateHCID 3028194LithiumHCID 15389071HCID 15389071, compound

Product 1

HCID 23708083HCID 23708083, compound

Procedure

In a similar manner to Example 10, by reaction of 200 mg (5.5 mmol) of 2-hydroxy-4-[3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propynyl]benzoic acid with 23 mg (5.5 mmol) of lithium hydroxide hydrate, 150 mg (74%) of the expected lithium salt are obtained, with a melting point of 225-9° C.

Workup

  1. customare obtained, with a melting point of 225-9° C.

Sources & evidence

ORD record
ord-60e161cdc24746699584e67dca2d6a35
Source dataset
uspto-grants-2001_11
Patent number
US06313162B1

Reaction notes

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