Hydrochloric Acid → HCID 18353696, compound

HRID 430076Notes

Reaction equation

HRID 430076 reaction equation
[NH2:1][CH2:2][C:3](=[CH2:18])[CH2:4][NH:5][C:6]1[CH:15]=[C:14]([O:16]C)[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1.[ClH:19]>>[ClH:19].[ClH:19].[NH2:1][CH2:2][C:3](=[CH2:18])[CH2:4][NH:5][C:6]1[NH:7][C:8]2[C:13]([C:14](=[O:16])[CH:15]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 18353694HCID 18353694, compound

Product 1

HCID 18353696HCID 18353696, compound

Procedure

The title compound was prepared according to the method described in Example 1(b) from 2-(2-aminomethylallylamino)-4-methoxyquinoline (70 mg, 0.29 mmol) and concentrated hydrochloric acid (2 mL) and was used without further purification. δH (CD3OD) 3.92 (2H, s), 4.53 (2H, s), 5.59 (2H, d, J=12.8), 6.61 (1H, d, J=0.9 Hz.), 7.65 (1H, dd, J=7.18 & 7.12 Hz), 7.93 (1H, dd, J=7.21 & 7.23 Hz), 8.02-8.16 (1H, m), 8.25 (1H, d, J=8.08 Hz); MS (ES+) 230 (31%) MH+ 213 (100%).

Workup

  1. customwas used without further purification

Sources & evidence

ORD record
ord-d6d1e8ea8b6a49d38c549348f601ceb8
Source dataset
uspto-grants-2001_11
Patent number
US06320051B1

Reaction notes

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