Ammonium formate → HCID 18351386, compound

HRID 430617Notes

Reaction equation

HRID 430617 reaction equation
C([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][N:15]([CH3:33])[S:16]([C:19]2[CH:28]=[CH:27][CH:26]=[C:25]3[C:20]=2[CH2:21][CH2:22][N:23]([C:29]([O:31][CH3:32])=[O:30])[CH2:24]3)(=[O:18])=[O:17])[CH2:10][CH2:9]1)C1C=CC=CC=1.C([O-])=O.[NH4+]>CO.[Pd]>[NH:8]1[CH2:9][CH2:10][CH:11]([CH2:14][N:15]([CH3:33])[S:16]([C:19]2[CH:28]=[CH:27][CH:26]=[C:25]3[C:20]=2[CH2:21][CH2:22][N:23]([C:29]([O:31][CH3:32])=[O:30])[CH2:24]3)(=[O:18])=[O:17])[CH2:12][CH2:13]1

Participants

5

Reactant 2

HCID 2723923Ammonium formateHCID 18351353HCID 18351353, compound

Product 1

HCID 18351386HCID 18351386, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 5.6 g of the product obtained in Step C, 3.7 g of ammonium formate and 0.56 g of 10% Pd/C in 120 ml of methanol is refluxed for 3 hours, then filtered over Celite and evaporated to dryness, enabling the expected product to be isolated.

Workup

  1. temperatureis refluxed for 3 hours
  2. filtrationfiltered over Celite
  3. customevaporated to dryness
  4. customto be isolated

Sources & evidence

ORD record
ord-7c14a3e104914c16872d0a4dccd478a2
Source dataset
uspto-grants-2001_11
Patent number
US06323217B2

Reaction notes

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