Benzaldehyde → N,N-di-n-propylbenzylamine

HRID 430857Notes

Reaction equation

HRID 430857 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:9]([NH:12][CH2:13][CH2:14][CH3:15])[CH2:10][CH3:11]>ClCCl>[CH2:9]([N:12]([CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:13][CH2:14][CH3:15])[CH2:10][CH3:11]

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 8902Dipropylamine

Product 1

HCID 9794124N,N-di-n-propylbenzylamine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Benzaldehyde (0.404 cm3, 4.0 mmol), di-n-propylamine (0.548 cm3, 4.0 mmol) and [Ir(COD)(dppb)][PF6] (0.070 g, 2 mol %) in dichloromethane were treated as stated above under approx 1 bar H2 at approx. 20° C. for 3 hrs. The yield of N,N-di-n-propylbenzylamine obtained was 39.6%.

Sources & evidence

ORD record
ord-0fdce03e711c4bd2927dfbdc8c2bc9cb
Source dataset
uspto-grants-2001_11
Patent number
US06323370B1

Reaction notes

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