2-Pyridinecarboxaldehyde → HCID 22335562, compound

HRID 431197Notes

Reaction equation

HRID 431197 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH:7]1([N+:13]#[C-:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1.[N:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[CH:21]=O>Cl(O)(=O)(=O)=O>[CH:7]1([NH:13][C:14]2[N:3]3[NH:4][CH:5]=[N:6][C:2]3=[N:1][C:21]=2[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][N:15]=2)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1

Participants

5

Reactant 3

HCID 142732-PyridinecarboxaldehydeHCID 79129Cyclohexyl isocyanideHCID 178418311HCID 178418311, compound

Product 1

HCID 22335562HCID 22335562, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound 11 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2-pyridinecarbaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

Sources & evidence

ORD record
ord-8cd9914fab624f1bb354716cd8c738d7
Source dataset
uspto-grants-2003_12
Patent number
US06657064B2

Reaction notes

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