Hydrochloric Acid → HCID 18763410, compound

HRID 431373Notes

Reaction equation

HRID 431373 reaction equation
[Li+].[OH-].C[O:4][C:5](=[O:27])[C:6]1[CH:15]=[C:14]([O:16][C:17]2[CH:26]=[CH:25][C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH:18]=2)[CH:13]=[C:8]([C:9]([O:11]C)=[O:10])[CH:7]=1.Cl>O.CCO>[CH:18]1[C:19]2[C:24](=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:25]=[CH:26][C:17]=1[O:16][C:14]1[CH:13]=[C:8]([C:9]([OH:11])=[O:10])[CH:7]=[C:6]([CH:15]=1)[C:5]([OH:27])=[O:4]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 20607511HCID 20607511, compound

Product 1

HCID 18763410HCID 18763410, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A solution of LiOH (1.5 mmol) in water (1 ml) was added to 5-(naphthalene-2-yloxy)-isophthalic acid dimethylester (0.5 mmol) suspended in 5 ml EtOH. The mixture was stirred at room temperature. The reaction was monitored by TLC until completion. 2.5 ml 1 M HCl solution was added and the precipitation was collected. The product was used in next step without further purification.

Workup

  1. customthe precipitation
  2. customwas collected
  3. customThe product was used in next step without further purification

Sources & evidence

ORD record
ord-e4fd4355cff4487ab8fd3e7aa9e9c9a3
Source dataset
uspto-grants-2003_12
Patent number
US06656971B2

Reaction notes

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