Hydrochloric Acid → HCID 20493940, compound

HRID 434393Notes

Reaction equation

HRID 434393 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH3:17][S:18]([NH:21][C:22]1[C:31]2[C:26](=[CH:27][CH:28]=[C:29]([S:32](Cl)(=[O:34])=[O:33])[CH:30]=2)[C:25]([N:36]=[N:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=2[C:44]#[N:45])=[CH:24][CH:23]=1)(=[O:20])=[O:19].Cl>O.CC(C)=O>[CH3:17][S:18]([NH:21][C:22]1[C:31]2[C:26](=[CH:27][CH:28]=[C:29]([S:32](=[O:34])(=[O:33])[NH:1][C:2]3[CH:7]=[CH:6][C:5]([S:8]([OH:10])=[O:9])=[CH:4][CH:3]=3)[CH:30]=2)[C:25]([N:36]=[N:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=2[C:44]#[N:45])=[CH:24][CH:23]=1)(=[O:20])=[O:19]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 3450564-Aminobenzenesulfinic acidHCID 20493938HCID 20493938, compound

Product 1

HCID 20493940HCID 20493940, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent2×

Procedure

To a solution of 52.5 g of p-aminobenzene sulphinic acid and 96 g of potassium carbonate in 850 ml of water first 1 l of acetone was added and then portionwise 157 g of compound P with stirring. Thereupon, the mixture was stirred for 1 h, poured into 2.5 l of water and acidified with 100 ml of concentrated hydrochloric acid. The precipitate formed was sucked off, washed with methanol and dried. Yield: 160 g.

Workup

  1. customThe precipitate formed
  2. washwashed with methanol
  3. customdried

Sources & evidence

ORD record
ord-70ff2ca5eb964e17aecc49ce623da4ea
Source dataset
uspto-grants-1983_08
Patent number
US04396699

Reaction notes

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