反应详情

Into a mixture of 87 gm of N-ethylacetamide and 82 gm of phosphorous acid, hydrogen chloride was introduced for 8 hours. During this time the mixture was stirred and the temperature was held at 150° - 160° C. The reaction mixture was then treated analogously to Example 1, and the N-ethyl-1-aminoethane- 1,1 -diphosphonic acid product was obtained. The yield was 36.5 gm.

1. additionwas introduced for 8 hours
2. customwas held at 150° - 160° C
3. additionThe reaction mixture was then treated analogously to Example 1