反应详情

温度

12 °C

Thirty grams (1.0 mole) paraformaldehyde was added to a solution of 89.2 g. (1.0 mole) 2-amino-2-methyl-1-propanol in 600 ml. isopropanol, temperature at 45°-64° C. After all the paraformaldehyde had dissolved, the mixture was cooled to 12° C.; 92 g. (0.50 mole) anhydrous zinc acetate and 76 g. (1.0 mole) carbon disulfide were added. The reaction mixture was stirred 6 hours at 45°-50° C. Filtration at 5° C. gave 152.6 g. of the desired product melting with decomposition at 209°-211° C. A benzene-crystallized sample had the following analysis: Found: C, 34.92; H, 4.91; N, 6.62; Zn, 15.47. Calc. for C12H20N2O2S4Zn: C, 34.50; H, 4.79; N, 6.71; Zn, 15.67.

1. customat 45°-64° C
2. filtrationFiltration at 5° C.
3. customgave 152.6 g