Resorcinol → HCID 135726678, compound

HRID 436309Notes

Reaction equation

HRID 436309 reaction equation
[S-:1][C:2]#[N:3].[K+].[C:5]1([CH:12]=[CH:11][CH:10]=[C:8]([OH:9])[CH:7]=1)[OH:6].F>>[OH:6][C:5]1[CH:7]=[C:8]([OH:9])[CH:10]=[CH:11][C:12]=1[C:2]([NH2:3])=[S:1]

Participants

4

Reactant 3

HCID 5054ResorcinolHCID 14917Hydrofluoric AcidHCID 516872Potassium thiocyanate

Product 1

HCID 135726678HCID 135726678, compoundYield 80%

Procedure

At a temperature and in the manner as described in Example 1, 39 g of potassium thiocyanate (0.4 mol) and 38.5 g of resorcinol (0.35 mol) are stirred with 0.3 l of 98% hydrofluoric acid, and subsequently, the mixture is stirred for 5 hours at room temperature. 0.25 l of hydrofluoric acid are then distilled off, and the residue is mixed with a small amount of ice, which causes 47 g of 2,4-dihydroxy-thiobenzamide to crystallize. This corresponds to a yield of 80% of the theoretical yield, relative to the resorcinol used. The melting point is 164° - 166° C.

Workup

  1. distillation0.25 l of hydrofluoric acid are then distilled off
  2. additionthe residue is mixed with a small amount of ice, which
  3. customto crystallize

Sources & evidence

ORD record
ord-0ebae922d4a5432fb54af668d0f55802
Source dataset
uspto-grants-1977_02
Patent number
US04008264

Reaction notes

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