Hydrochloric Acid → HCID 21454470, compound

HRID 436378Notes

Reaction equation

HRID 436378 reaction equation
[C:1]1([NH:11][C:12]([NH:14][CH2:15][C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)=[O:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[ClH:22]>C(Cl)(Cl)Cl>[ClH:22].[C:1]1([NH:11][C:12]([NH:14][CH2:15][C:16]2[CH:17]=[CH:18][N:19]=[CH:20][CH:21]=2)=[O:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 9150381-naphthalen-1-yl-3-(pyridin-4-ylmethyl)urea

Product 1

HCID 21454470HCID 21454470, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution of 2.77 gm. (0.01 mole) of 1-(1-naphthyl)-3-(4-pyridylmethyl)urea and 50 ml. of chloroform is saturated with anhydrous hydrogen chloride. The solution is then evaporated to dryness in vacuo. The residue is crystallized from alcohol Skellysolve B (9:1 v/v) to give 1-(1-naphthyl)-3-(4-pyridylmethyl)urea hydrochloride.

Workup

  1. customThe solution is then evaporated to dryness in vacuo
  2. customThe residue is crystallized from alcohol Skellysolve B (9:1 v/v)

Sources & evidence

ORD record
ord-96be6f5ff3d54d1ab89852d29dec29f0
Source dataset
uspto-grants-1977_02
Patent number
US04008326

Reaction notes

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