反应详情

In a manner similar to that of Example 4, condensation of 1-hydrazino-3,4-dihydroisoquinoline (5.7 g.) and 2,3-dimethoxybenzaldehyde (6.17 g.) and treatment of the reaction mixture with hydrochloric acid gave a solid, which was recrystallized twice from ethanol, affording 1-[2-(2,3-dimethoxybenzylidene)-hydrazino]-3,4-dihydroisoquinoline (I: X=2,3-(CH3O)2C6H3, X'=Y=Y'=Z=Z'=H) hydrochloride (8.2 g., m.p. 222°-223° C.).

1. customgave a solid, which
2. customwas recrystallized twice from ethanol