Hydrochloric Acid → HCID 21430592, compound

HRID 437244Notes

Reaction equation

HRID 437244 reaction equation
Cl.[CH2:2]1[C:11]2[C:6](=[CH:7][C:8]([C:12](=[O:29])[CH2:13][N:14]3[CH2:19][CH2:18][CH:17]([NH:20][C:21](=[O:28])[C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)[CH2:16][CH2:15]3)=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH2:3]1.[BH4-].[Na+]>>[CH2:2]1[C:11]2[C:6](=[CH:7][C:8]([CH:12]([OH:29])[CH2:13][N:14]3[CH2:19][CH2:18][CH:17]([NH:20][C:21](=[O:28])[C:22]4[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=4)[CH2:16][CH2:15]3)=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH2:3]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 4311764Sodium borohydrideHCID 21430568HCID 21430568, compound

Product 1

HCID 21430592HCID 21430592, compound

Procedure

The title compound as its hydrochloride, m.p. 253° C. (decomp.), was prepared by reduction of the free base of the compound obtained in Example 56 using sodium borohydride. The procedure is that described in Example 53. (Found: C, 69.7; H, 7.5; N, 6.6. C24H30N2O2.HCl requires C, 69.5; H, 7.5; N, 6.75%).

Sources & evidence

ORD record
ord-7339a6bd650c44558a7b5951cd37e511
Source dataset
uspto-grants-1977_06
Patent number
US04029801

Reaction notes

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