Methyl fluorosulfate → HCID 86734872, compound

HRID 437320Notes

Reaction equation

HRID 437320 reaction equation
[CH2:1]([N:3]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:12])[CH3:2].[F:13][S:14]([O:17][CH3:18])(=[O:16])=[O:15]>C(Cl)Cl>[F:13][S:14]([O-:17])(=[O:16])=[O:15].[CH2:1]([N+:3]1[CH2:11][C:10]2[C:5]([C:4]=1[O:12][CH3:18])=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH3:2]

Participants

4

Reactant 2

HCID 9870Methyl fluorosulfateHCID 119619081H-Isoindol-1-one, 2-ethyl-2,3-dihydro-

Product 1

HCID 86734872HCID 86734872, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-ethyl-1-(3H)-isoindolone (1.6 g) was dissolved in dry methylene chloride, and methyl fluorosulfonate (1.2 g) was was added. The reaction mixture was stirred for 30 minutes and then evaporated to dryness. The resuling oil was triturated with acetonitrile and ether. The solid intermediate compound was collected by filtration and used for preparing dyes without further purification.

Workup

  1. customevaporated to dryness
  2. customThe resuling oil was triturated with acetonitrile and ether
  3. filtrationThe solid intermediate compound was collected by filtration
  4. customused for preparing dyes without further purification

Sources & evidence

ORD record
ord-54f02ba6815042fdad72e15d069fd49e
Source dataset
uspto-grants-1977_06
Patent number
US04030932

Reaction notes

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