反应详情

A stirred mixture of salicylamide (10.02 g., 0.074 mole), potassium carbonate (10.24 g., 0.074 mole) and bromomethylcyclopropane (10.0 g., 0.074 mole) in ethanol (15 ml.) was heated under reflux for 19 hours. The mixture was concentrated and the residue treated with water. The mixture was filtered and the collected solid recrystallized from benzene-Skellysolve B to give 2-cyclopropylmethoxybenzamide (10.0 g., 71.6%), m.p. 102°-105°.

1. temperaturewas heated
2. temperatureunder reflux for 19 hours
3. concentrationThe mixture was concentrated
4. additionthe residue treated with water
5. filtrationThe mixture was filtered
6. customthe collected solid recrystallized from benzene-Skellysolve B