HCID 20371578, compound → HCID 20434099, compound

HRID 437908Notes

Reaction equation

HRID 437908 reaction equation
[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([CH:27]=[CH:28][C:29]=1[O:30][CH3:31])[CH2:7][CH2:8][NH:9][CH2:10][CH:11]([OH:26])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18]CC1C=CC=CC=1>[C].[Pd].C(O)(C)C>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([CH:27]=[CH:28][C:29]=1[O:30][CH3:31])[CH2:7][CH2:8][NH:9][CH2:10][CH:11]([OH:26])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[OH:18]

Participants

4

Reactant 1

HCID 20371578HCID 20371578, compound

Product 1

HCID 20434099HCID 20434099, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 3776IsopropanolSolvent

Procedure

One g of α-(3,4-dimethoxyphenethylaminomethyl)-2-benzyloxybenzylalcohol hydrochloride, 0.3 g of 10 % palladium-carbon and 30 ml of 80 % aqueous isopropanol are treated in the same manner as described in Example 1-(c). 0.75 g of α-(3,4-dimethoxyphenethylaminomethyl)-2-hydroxybenzylalcohol hydrochloride are obtained. M.p. 141° - 143° C.(decomp.)(recrystallized from a mixture of ethanol and ether). 1/2 Oxalate: M.p. 175° -176° C.(recrystallized from ethanol).

Sources & evidence

ORD record
ord-954c8ded364b4b9cac88d3d16da39418
Source dataset
uspto-grants-1977_06
Patent number
US04032575

Reaction notes

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