Methanol → HCID 54044653, compound

HRID 438003Notes

Reaction equation

HRID 438003 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[NH2:13][C@H:14]([C:20]([OH:22])=[O:21])[CH2:15][CH2:16][C:17]([OH:19])=[O:18].CO>[Ni].[Pd].O>[OH:4][CH:3]([CH:5]([OH:6])[CH:7]([OH:8])[CH:9]([OH:10])[CH2:11][OH:12])[CH2:2][NH:13][C@H:14]([C:20]([OH:22])=[O:21])[CH2:15][CH2:16][C:17]([OH:19])=[O:18]

Participants

7

Reactant 3

HCID 887MethanolHCID 33032L-Glutamic AcidHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 54044653HCID 54044653, compound

Reagents, catalysts & solvents 3

HCID 935NickelCatalystHCID 23938PalladiumCatalystHCID 962WaterSolvent

Procedure

The product was made from D-glucose and L-(+)-glutamic acid using Raney nickel or palladium/activated carbon (10%) as a catalyst. The product had a melting point of 94° C. and an RF -value of 0.61 (determined on DC-finished plates of silica gel G (Merck) with a transporting fluid made up of 85 parts by volume of methanol and 15 parts by volume of water).

Sources & evidence

ORD record
ord-4eb0997309fe4736bea4767a9e210335
Source dataset
uspto-grants-1977_06
Patent number
US04032676

Reaction notes

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