4-Aminobenzoic Acid → HCID 21427706, compound

HRID 438015Notes

Reaction equation

HRID 438015 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[NH2:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=1>[Ni]>[OH:4][CH:3]([CH:5]([OH:6])[CH:7]([OH:8])[CH:9]([OH:10])[CH2:11][OH:12])[CH2:2][NH:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 9784-Aminobenzoic AcidHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 21427706HCID 21427706, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

As starting materials D-glucose and p-amino-benzoic acid were used. The reductive amination was carried out using Raney nickel as catalyst and heating for 2 hours to 50° C. and for 3 hours to 70° C. The product obtained had a melting point of 111° to 112° C.

Workup

  1. temperatureheating for 2 hours to 50° C. and for 3 hours to 70° C
  2. customThe product obtained

Sources & evidence

ORD record
ord-0f24c802f0804449a26f33f75999df83
Source dataset
uspto-grants-1977_06
Patent number
US04032676

Reaction notes

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