7-Nitrobenzofuran-3(2H)-one → 7-Amino-2,3-dihydro-3-benzofuranone

HRID 440673Notes

Reaction equation

HRID 440673 reaction equation
[N+:1]([C:4]1[C:12]2[O:11][CH2:10][C:9](=[O:13])[C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-])=O>C(O)(=O)C.O.[Fe]>[NH2:1][C:4]1[C:12]2[O:11][CH2:10][C:9](=[O:13])[C:8]=2[CH:7]=[CH:6][CH:5]=1

Participants

5

Reactant 1

HCID 224047597-Nitrobenzofuran-3(2H)-one

Product 1

HCID 224048037-Amino-2,3-dihydro-3-benzofuranone

Reagents, catalysts & solvents 3

HCID 23925IronCatalystHCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

By the method of Example 1, Step E, 2.51 g (0.014 mole) of 2,3-dihydro-7-nitro-3-benzofuranone is reacted with 3.1 g (0.056 mole) of powdered iron in 45 mL of glacial acetic acid and 8 mL of water, yielding 7-amino-2,3-dihydro-3-benzofuranone.

Sources & evidence

ORD record
ord-6bbcd3de47fa4104a578b6032fb06ea1
Source dataset
uspto-grants-1996_05
Patent number
US05521147

Reaction notes

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