Chlorosuccinimide → 7-Amino-4-chloro-2,3-dihydro-3-benzofuranone

HRID 440674Notes

Reaction equation

HRID 440674 reaction equation
[NH2:1][C:2]1[C:10]2[O:9][CH2:8][C:7](=[O:11])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[Cl:12]N1C(=O)CCC1=O>CN(C)C=O>[NH2:1][C:2]1[C:10]2[O:9][CH2:8][C:7](=[O:11])[C:6]=2[C:5]([Cl:12])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 224048037-Amino-2,3-dihydro-3-benzofuranone

Product 1

HCID 224047997-Amino-4-chloro-2,3-dihydro-3-benzofuranone

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

By the method of Example 3, Step C, 1.94 g (0.013 mole) of 7-amino-2,3-dihydro-3-benzofuranone and 1.74 g (0.013 mole) of N-chlorosuccinimide are reacted in 40 mL of N,N-dimethylformamide, yielding 7-amino-4-chloro-2,3-dihydro-3-benzofuranone.

Sources & evidence

ORD record
ord-769ea73306a14e74934046ea6e61c7ca
Source dataset
uspto-grants-1996_05
Patent number
US05521147

Reaction notes

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