Chlorosuccinimide → HCID 22404764, compound

HRID 440678Notes

Reaction equation

HRID 440678 reaction equation
[NH2:1][C:2]1[C:10]2[O:9][C:8]([CH3:12])([CH3:11])[C:7](=[S:13])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[Cl:14]N1C(=O)CCC1=O>CN(C)C=O>[NH2:1][C:2]1[C:10]2[O:9][C:8]([CH3:11])([CH3:12])[C:7](=[S:13])[C:6]=2[C:5]([Cl:14])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 22404732HCID 22404732, compound

Product 1

HCID 22404764HCID 22404764, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

By the method of Example 3, Step C, 2.51 g (0.013 mole) of 7-amino-2,3-dihydro-2,2-dimethylbenzofuran-3-thione is reacted with 1.74 g (0.013 mole) of N-chlorosuccinimide in 35 mL of N,N-dimethylformamide, yielding 7-amino-4-chloro-2,3-dihydro-2,2-dimethylbenzofuran-3-thione.

Sources & evidence

ORD record
ord-5a49469e7ef04c868f6311d7826029a9
Source dataset
uspto-grants-1996_05
Patent number
US05521147

Reaction notes

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