Potassium Iodide → HCID 515414, compound

HRID 441647Notes

Reaction equation

HRID 441647 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]1[CH:21]=[CH:20][C:19]2[S:18][C:17]3[C:12](=[CH:13][C:14]([C:22](=[O:28])[CH2:23][CH2:24][CH2:25][CH2:26]Cl)=[CH:15][CH:16]=3)[CH2:11][C:10]=2[CH:9]=1)=[O:7].[I-].[K+].[NH:31]1[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1>O1CCCC1>[N:31]1([CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:8]2[CH:21]=[CH:20][C:19]3[S:18][C:17]4[C:12](=[CH:13][C:14]([C:22](=[O:28])[CH2:23][CH2:24][CH2:25][CH2:26][N:31]5[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]5)=[CH:15][CH:16]=4)[CH2:11][C:10]=3[CH:9]=2)=[O:7])[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1

Participants

5

Reactant 3

HCID 4875Potassium IodideHCID 8082PiperidineHCID 12340289HCID 12340289, compound

Product 1

HCID 515414HCID 515414, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 20 g of 2,7-bis(5-chlorovaleryl)thioxanthene, 2 g of potassium iodide, 70 ml of piperidine and 150 ml of tetrahydrofuran is heated in a Paar bomb at 100° C. with stirring for 48 hours. Upon cooling, the solvent is evaporated, and the remaining material is poured into water then filtered. The residue is recrystallized several times from heptane to give 2,7-bis(5-piperidinovaleryl)thioxanthene, M.P. 98.5°-99.5° C.

Workup

  1. temperatureUpon cooling
  2. customthe solvent is evaporated
  3. additionthe remaining material is poured into water
  4. filtrationthen filtered
  5. customThe residue is recrystallized several times from heptane

Sources & evidence

ORD record
ord-41ac9aef9055469b830926951bf08d42
Source dataset
uspto-grants-1977_08
Patent number
US04041165

Reaction notes

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