Dimethylformamide → HCID 178522700, compound

HRID 441662Notes

Reaction equation

HRID 441662 reaction equation
[C:1]([C:4]1[C:12](=[O:13])[N:11]2[C:7]([S:8][C:9]3[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=32)=[N:6][CH:5]=1)([OH:3])=O.[C:18](N1C=CN=C1)(N1C=CN=C1)=[O:19].[NH2:30][C:31]1[NH:35][N:34]=[N:33][N:32]=1.CN(C)[CH:38]=[O:39]>>[NH:32]1[C:31]([NH:30][C:1]([C:4]2[C:12](=[O:13])[N:11]3[C:7]([S:8][C:9]4[CH:17]=[C:16]5[O:19][CH2:18][CH2:38][O:39][C:15]5=[CH:14][C:10]=43)=[N:6][CH:5]=2)=[O:3])=[N:35][N:34]=[N:33]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 682631,1'-CarbonyldiimidazoleHCID 27258594-Oxo-4H-9-thia-1,4a-diaza-fluorene-3-carboxylic acidHCID 178509299HCID 178509299, compound

Product 1

HCID 178522700HCID 178522700, compound

Procedure

Again, in a manner similar to Example 21, the desired product is prepared from 880 ml. of 3-carboxy-4-oxo-4H-pyrimido[2,1-b]benzothiazole, 535 mg. of 1,1'-carbonyldiimidazole and 281 mg. of 5-aminotetrazole in 40 ml. of dimethylformamide.

Sources & evidence

ORD record
ord-af3b050a11724ee188ea3289030793d4
Source dataset
uspto-grants-1977_08
Patent number
US04041163

Reaction notes

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